{"product_id":"credelio-plus-caini-1-comprimat-masticabil","title":"Credelio Plus pentru Caini 1 Comprimat Masticabil","description":"\u003cspan style=\"font-size:14px;\"\u003eDENUMIREA PRODUSULUI MEDICINAL VETERINAR\u003cbr\u003e \u003cbr\u003e Credelio Plus 56,25 mg\/2,11 mg comprimate masticabile pentru caini (1,4–2,8 kg)\u003cbr\u003e Credelio Plus 112,5 mg\/4,22 mg comprimate masticabile pentru caini (\u0026gt;2,8–5,5 kg)\u003cbr\u003e Credelio Plus 225 mg\/8,44 mg comprimate masticabile pentru caini (\u0026gt;5,5–11 kg)\u003cbr\u003e Credelio Plus 450 mg\/16,88 mg comprimate masticabile pentru caini (\u0026gt;11–22 kg)\u003cbr\u003e Credelio Plus 900 mg\/33,75 mg comprimate masticabile pentru caini (\u0026gt;22–45 kg)\u003cbr\u003e \u003cbr\u003e 2. COMPOZITIA CALITATIVA SI CANTITATIVA\u003cbr\u003e \u003cbr\u003e Substante active:\u003cbr\u003e Fiecare comprimat masticabil contine:\u003cbr\u003e \u003cbr\u003e Pentru lista completa a excipientilor, vezi sectiunea 6.1.\u003cbr\u003e \u003cbr\u003e 3. FORMA FARMACEUTICA\u003cbr\u003e \u003cbr\u003e Comprimat masticabil.\u003cbr\u003e \u003cbr\u003e Comprimat masticabil rotund, biconvex, alb spre bej, cu puncte maronii si muchii tesite, cu litera „I” inscriptionata pe o parte a comprimatului.\u003cbr\u003e \u003cbr\u003e 4. PARTICULARITATI CLINICE\u003cbr\u003e \u003cbr\u003e 4.1 SPECII TINTA\u003cbr\u003e Caini\u003cbr\u003e \u003cbr\u003e 4.2 Indicatii pentru utilizare, cu specificarea speciilor tinta\u003cbr\u003e \u003cbr\u003e Pentru utilizare la caini cu sau expusi riscului de infestari\/infectii mixte cu capuse, purici, acarieni, nematode gastrointestinale, viermi cardiaci si\/sau viermi pulmonari.\u003cbr\u003e \u003cbr\u003e Acest produs medicinal veterinar este indicat pentru utilizare atunci cand tratamentul impotriva capuselor\/puricilor\/acarienilor si nematodelor gastrointestinale sau tratamentul impotriva capuselor\/puricilor\/acarienilor si prevenirea dirofilariozei\/angiostrongilozei sunt necesare concomitent.\u003cbr\u003e \u003cbr\u003e Ectoparaziti\u003cbr\u003e Pentru tratamentul infestarilor cu capuse (Dermacentor reticulatus, Ixodes ricinus, Rhipicephalus sanguineus si I. hexagonus) si cu purici (Ctenocephalides felis si C. canis) la caini.\u003cbr\u003e \u003cbr\u003e Acest produs medicinal veterinar ofera o activitate de distrugere imediata si persistenta a capuselor si puricilor pentru o perioada de 1 luna.\u003cbr\u003e \u003cbr\u003e Produsul medicinal veterinar poate fi utilizat ca parte a unei strategii de tratament pentru controlul dermatitei alergice provocate de purici (DAP).\u003cbr\u003e \u003cbr\u003e Credelio Plus comprimate lotilaner milbemicin oxima:\u003cbr\u003e \u003cbr\u003e Caini (1,4–2,8 kg) – 56,25 mg \/ 2,11 mg\u003cbr\u003e Caini (\u0026gt;2,8–5,5 kg) – 112,5 mg \/ 4,22 mg\u003cbr\u003e Caini (\u0026gt;5,5–11 kg) – 225 mg \/ 8,44 mg\u003cbr\u003e Caini (\u0026gt;11–22 kg) – 450 mg \/ 16,88 mg\u003cbr\u003e Caini (\u0026gt;22–45 kg) – 900 mg \/ 33,75 mg\u003cbr\u003e \u003cbr\u003e Pentru tratamentul demodicozei (cauzate de Demodex canis).\u003cbr\u003e \u003cbr\u003e Nematode gastrointestinale\u003cbr\u003e \u003cbr\u003e Tratamentul nematodelor gastrointestinale: viermi cu carlig (Ancylostoma caninum L4, adult imatur (L5) si adult), viermi inelati (Toxocara canis L4, adult imatur (L5) si adult si Toxascaris leonina adult) si viermi bici (Trichuris vulpis adult).\u003cbr\u003e \u003cbr\u003e Viermi cardiaci\u003cbr\u003e Prevenirea dirofilariozei (Dirofilaria immitis).\u003cbr\u003e \u003cbr\u003e Viermi pulmonari\u003cbr\u003e Prevenirea angiostrongilozei prin reducerea nivelului infectiei cu Angiostrongylus vasorum (vierme pulmonar) in stadiul adult imatur (L5) si adult, cu administrare lunara.\u003cbr\u003e \u003cbr\u003e 4.3 Contraindicatii\u003cbr\u003e \u003cbr\u003e Nu se utilizeaza in cazurile de hipersensibilitate cunoscuta la substantele active sau la oricare dintre excipienti.\u003cbr\u003e \u003cbr\u003e 4.4 Atentionari speciale pentru fiecare specie tinta\u003cbr\u003e \u003cbr\u003e Toti cainii din gospodarie trebuie tratati cu un produs adecvat.\u003cbr\u003e \u003cbr\u003e Capusele si puricii trebuie sa se aseze pe gazda si sa inceapa hranirea pentru a fi expusi la substanta activa; prin urmare, riscul transmiterii de boli transmisibile prin capuse\/purici nu poate fi exclus.\u003cbr\u003e \u003cbr\u003e Rezistenta parazitara la orice clasa specifica de antihelmintic poate aparea dupa utilizarea frecventa, repetata a unui antihelmintic din acea clasa. Prin urmare, utilizarea acestui produs medicinal veterinar trebuie sa se bazeze pe evaluarea fiecarui caz individual si pe informatiile epidemiologice locale cu privire la susceptibilitatea curenta a speciilor tinta, pentru a limita posibilitatea unei selectii viitoare pentru rezistenta.\u003cbr\u003e \u003cbr\u003e Pentru tratamentul infectiilor cu nematode gastrointestinale, nevoia de a relua tratamentul si frecventa cu care tratamentul este reluat, precum si alegerea tratamentului trebuie evaluate de catre medicul veterinar.\u003cbr\u003e \u003cbr\u003e Mentinerea eficacitatii lactonelor macrociclice este esentiala pentru profilaxia Dirofilaria immitis; se recomanda testarea cainilor pentru antigeni circulanti si microfilarii inainte de tratamentele profilactice.\u003cbr\u003e \u003cbr\u003e 4.5 Precautii speciale pentru utilizare\u003cbr\u003e \u003cbr\u003e La animale:\u003cbr\u003e Utilizarea la catei sub 8 saptamani sau sub 1,4 kg trebuie evaluata de medicul veterinar.\u003cbr\u003e \u003cbr\u003e Respectati doza la cainii cu mutatie MDR1 (-\/-).\u003cbr\u003e \u003cbr\u003e Testarea pentru dirofilarioza este necesara in zone endemice.\u003cbr\u003e \u003cbr\u003e Pentru persoana care administreaza:\u003cbr\u003e Ingerarea accidentala poate cauza tulburari gastrointestinale.\u003cbr\u003e Pastrati comprimatele departe de copii.\u003cbr\u003e Spalati-va pe maini dupa manipulare.\u003cbr\u003e \u003cbr\u003e 4.6 Reactii adverse\u003cbr\u003e \u003cbr\u003e Semne gastrointestinale, letargie, prurit – mai putin frecvente.\u003cbr\u003e Semne neurologice – rare.\u003cbr\u003e \u003cbr\u003e Clasificare frecventa:\u003cbr\u003e \u003cbr\u003e foarte frecvente\u003cbr\u003e frecvente\u003cbr\u003e mai putin frecvente\u003cbr\u003e rare\u003cbr\u003e foarte rare\u003cbr\u003e \u003cbr\u003e 4.7 Utilizare in gestatie\/lactatie\u003cbr\u003e \u003cbr\u003e Nu este complet stabilita. Utilizare doar dupa evaluarea medicului veterinar.\u003cbr\u003e \u003cbr\u003e 4.8 Interactiuni\u003cbr\u003e \u003cbr\u003e Poate interactiona cu substante substrat gp-P (ex: digoxina).\u003cbr\u003e \u003cbr\u003e 4.9 Administrare\u003cbr\u003e \u003cbr\u003e Administrare orala.\u003cbr\u003e \u003cbr\u003e Doza:\u003cbr\u003e 20–41 mg lotilaner\/kg\u003cbr\u003e 0,75–1,53 mg milbemicin oxima\/kg\u003cbr\u003e \u003cbr\u003e Schema:\u003cbr\u003e \u003cbr\u003e 1,4–2,8 kg → 1 comprimat 56,25 mg\u003cbr\u003e \u003cbr\u003e 2,8–5,5 kg → 1 comprimat 112,5 mg\u003cbr\u003e \u003cbr\u003e 5,5–11 kg → 1 comprimat 225 mg\u003cbr\u003e \u003cbr\u003e 11–22 kg → 1 comprimat 450 mg\u003cbr\u003e \u003cbr\u003e 22–45 kg → 1 comprimat 900 mg\u003cbr\u003e \u003cbr\u003e 45 kg → combinatie comprimate\u003cbr\u003e \u003cbr\u003e Administrare lunara, cu sau dupa masa.\u003cbr\u003e \u003cbr\u003e Indicatii speciale:\u003cbr\u003e \u003cbr\u003e tratament sezonier purici\/capuse\u003cbr\u003e profilaxie dirofilarioza\u003cbr\u003e tratament demodicoza (minim 2 luni)\u003cbr\u003e prevenire angiostrongiloza\u003cbr\u003e \u003cbr\u003e 4.10 Supradozare\u003cbr\u003e \u003cbr\u003e Nu au fost observate reactii adverse semnificative pana la 5–6 ori doza.\u003cbr\u003e \u003cbr\u003e 4.11 Timp de asteptare\u003cbr\u003e \u003cbr\u003e Nu este cazul.\u003cbr\u003e \u003cbr\u003e 5. PROPRIETATI FARMACOLOGICE\u003cbr\u003e \u003cbr\u003e Grupa: antiparazitare sistemice\u003cbr\u003e Cod ATC: QP54AB51\u003cbr\u003e \u003cbr\u003e 5.1 Farmacodinamica\u003cbr\u003e \u003cbr\u003e Lotilaner – insecticid si acaricid (izoxazoline)\u003cbr\u003e Actioneaza asupra canalelor GABA → moartea parazitilor\u003cbr\u003e \u003cbr\u003e Eficacitate:\u003cbr\u003e \u003cbr\u003e purici: 4–6 ore\u003cbr\u003e capuse: 8–48 ore\u003cbr\u003e \u003cbr\u003e Milbemicin oxima – endectocid\u003cbr\u003e Actioneaza asupra neurotransmisiei → paralizie paraziti\u003cbr\u003e \u003cbr\u003e 5.2 Farmacocinetica\u003cbr\u003e \u003cbr\u003e Absorbtie rapida (3–5 ore)\u003cbr\u003e Biodisponibilitate crescuta cu hrana\u003cbr\u003e \u003cbr\u003e Distribuire mare, legare \u0026gt;95%\u003cbr\u003e \u003cbr\u003e Eliminare:\u003cbr\u003e \u003cbr\u003e bilara (principala)\u003cbr\u003e renala (\u0026lt;10%)\u003cbr\u003e \u003cbr\u003e Timp de injumatatire:\u003cbr\u003e \u003cbr\u003e lotilaner ~24 zile\u003cbr\u003e milbemicin 27–57 ore\u003cbr\u003e \u003cbr\u003e 6. PARTICULARITATI FARMACEUTICE\u003cbr\u003e \u003cbr\u003e 6.1 Excipienti:\u003cbr\u003e \u003cbr\u003e celuloza pulbere\u003cbr\u003e lactoza monohidrat\u003cbr\u003e celuloza microcristalina silicificata\u003cbr\u003e aroma carne\u003cbr\u003e crospovidona\u003cbr\u003e povidona K30\u003cbr\u003e laurilsulfat de sodiu\u003cbr\u003e dioxid de siliciu\u003cbr\u003e stearat de magneziu\u003cbr\u003e \u003cbr\u003e 6.2 Incompatibilitati\u003cbr\u003e Nu este cazul.\u003cbr\u003e \u003cbr\u003e 6.3 Valabilitate\u003cbr\u003e 3 ani\u003cbr\u003e \u003cbr\u003e 6.4 Depozitare\u003cbr\u003e Nu necesita conditii speciale.\u003c\/span\u003e","brand":"Elanco","offers":[{"title":"(1.3-2.5 kg) 56.25 mg","offer_id":53831790362961,"sku":"238048C.1","price":43.0,"currency_code":"RON","in_stock":true},{"title":"(2.8-5.5 kg) 112.5 mg","offer_id":53831790395729,"sku":"246102D.1","price":48.0,"currency_code":"RON","in_stock":true},{"title":"(5.5-11 kg) 225 mg","offer_id":53831790428497,"sku":"205842D.1","price":60.0,"currency_code":"RON","in_stock":true},{"title":"(11-22 kg) 450 mg","offer_id":53831790461265,"sku":"243730D.1","price":67.0,"currency_code":"RON","in_stock":true},{"title":"(22-45 kg) 900 mg","offer_id":53831790494033,"sku":"243725C.1","price":78.0,"currency_code":"RON","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1038\/9196\/0145\/files\/credelio-plus-pentru-caini-3-comprimate-masticabile-6072245370.webp?v=1779379084","url":"https:\/\/zoopoint.ro\/products\/credelio-plus-caini-1-comprimat-masticabil","provider":"ZooPoint","version":"1.0","type":"link"}